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Recombinant Human IL-5 (C-mFc)

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  • ¥1030 - 3100
  • 近岸蛋白(Novoprotein)已认证
  • CW78
  • 中国
  • 2025年11月02日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 英文名

      Recombinant Human IL-5 (C-mFc)

    • 规格

      10ug/50ug/500ug/1mg

    规格:10ug产品价格:¥1030.0
    规格:50ug产品价格:¥3100.0
    规格:500ug产品价格:询价
    规格:1mg产品价格:询价

    Recombinant Human IL-5 (C-mFc)(CW78)

     

    产品说明(Description)

    Recombinant Human Interleukin-5 is produced by our Mammalian expression system and the target gene encoding Ile20-Ser134 is expressed with a mFc tag at the C-terminus.

    Accession #: P05113

    Known as: Interleukin-5; IL-5; B-cell differentiation factor I; Eosinophil differentiation factor; T-cell replacing factor; TRF; IL5

     

    制剂(Formulation)

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

     

    质量控制(Quality Control) 

    Purity:            Greater than 95% as determined by reducing SDS-PAGE.    

    Endotoxin:    Less than 0.1 ng/ug (1 EU/ug) as determined by LAL test.

     

    复溶(Reconstitution)

    Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
    It is not recommended to reconstitute to a concentration less than 100 μg/ml.
    Dissolve the lyophilized protein in distilled water.
    Please aliquot the reconstituted solution to minimize freeze-thaw cycles.    

     

    保存(Storage)

    Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.

    Reconstituted protein solution can be stored at 4-7°C for 2-7 days.

    Aliquots of reconstituted samples are stable at < -20°C for 3 months.     

     

    背景(Background)

    IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functions on eosinophils. These include the down modulation of Mac-1,the upregulation of receptors for IgA and IgG,the stimulation of lipid mediator (leukotriene C4 and PAF) secretion and the induction of granule release.IL-5 also promotes the growth and differentiation of eosinophils.

     

    电泳(SDS-PAGE)

     

    FOR RESEARCH USE ONLY

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