Cell-Based PMA (1 mM)

【求助】sigma公司的PMA储存液浓度

licanming 请问大家用sigma公司的PMA时，储存液的浓度是配多少的？保存期多长？我是准备用DMSO配，我看说明书的意思是储存液浓度为20mM，但我工作液的浓度只要100nM，故很难分装和稀释。如果储存液浓度低一点，会不会对保存时间产生影响啊？我在园子里搜过，有用1mg/ml的，但我不知他是否用sigma公司的。 licanming 自己顶一下 amygdala 对于保存

MM-GB/SA Rescoring of Docking Poses

binding modes, but struggle when predicting the corresponding binding affinities. The rescoring of docking poses using the MM-GB/SA technique has emerged as an important computational approach in structure-based lead optimization as it provides

Estimation of the PPAR Agonism of Fibrates by a Combined MM-Docking Approach

for the investigation of the binding properties of fibrates, characterized by similar carboxylic heads but differing in the size and orientation of the hydrophobic portion. This procedure is based on a combination of standard docking and molecular mechanics approaches