Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) and COX-2 inhibitor (IC50s = 1.27 and 0.03 µM for the human and ovine enzymes, respectively).{1364,1286} It is selective for COX-2 over COX-1 (IC50s = 70 and 22 µM for the human and ovine enzy
英文名:
R805
库存:
1000 mg, 25000 mg, 5000 mg
供应商:
Cayman
CAS号:
51803-78-2
规格:
This biochemical is available in the following size(s) 1 mg, 10 mg, 5 mg - Please inquire
An NSAID and COX2 inhibitor (IC50s = 1.27 and 0.03 µM for the human and ovine enzymes, respectively); selective for COX-2 over COX-1 (IC50s = 70 and 22 µM for the human and ovine enzymes, respectively); inhibits B0AT1 (IC50 = 23 µM for the rat kidney transporter); inhibits infection-induced increases in brain PGE2 levels, and reduces pyresis (ED50 = 0.3 mg/kg), in yeast-infected rats; inhibits formalin-induced hindpaw thermal hyperalgesia in rats at 2.9 mg/kg