Tegoprazan is a proton pump inhibitor that inhibits H+/K+-ATPase activity in porcine gastric membrane vesicles (IC50 = 0.53 µM).{57515} It completely inhibits basal gastric acid secretion in pylorus-ligated rats when administered at a dose of 10 mg/kg a
英文名:
CJ-12420
库存:
1 mg, 10 mg, 25 mg, 5 mg
供应商:
Cayman
CAS号:
942195-55-3
规格:
This biochemical is available in the following size(s) 25 mg, 5 mg, 50 mg - Please inquire
A proton pump inhibitor (IC50 = 0.53 µM in porcine gastric membrane vesicles); inhibits basal gastric acid secretion in pylorus-ligated rats at 10 mg/kg; reduces esophageal mucosal tissue MPO levels in a rat model of reflux esophagitis (ED50 = 5.9 mg/kg); reduces ulcer area in rat models of naproxen-, WIRS-, or ethanol-induced gastric ulcers (ED50s = 0.1, 0.1, and 1.4 mg/kg, respectively)