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p21WAF1
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p21WAF1
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文献和实验Functional Analysis of CDK Inhibitor p21WAF1
p21WAF1 was originally identified as a protein that binds and inhibits cyclin-dependent kinases (CDKs). p21WAF1 is recognized to have at least two separate roles—first as a CDK inhibitor, and second as an inhibitor of PCNA, an accessory
Hepatocellular carcinoma (HCC) is one of the most common human malignancies in the world and it is especially prevalent in Asia and Africa (1 ). Some tumors are suitable for resection, however, there is a very high rate of recurrence
。 下图摘自Mathias, S et al Differential modulation of paclitaxel-mediated apoptosis by p21Waf1 and p27Kip1 Oncogene (2000) 19, 2423 -2429
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