SU 16f is a potent inhibitor of platelet-derived growth factor receptor β (PDGFRβ) with an IC50 value of 10 nM.{21720} It also inhibits VEGF receptor 2 (VEGFR2; IC50 = 140 nM). SU 16f selectively inhibits PDGF- over VEFG-, FGF-, and EGF-induced cell pro
英文名:
PDGFR Tyrosine Kinase Inhibitor VII
库存:
1 mg, 10 mg, 5 mg
供应商:
Cayman
CAS号:
251356-45-3
规格:
This biochemical is available in the following size(s) 5 mg - Please inquire
A potent inhibitor of PDGFRβ (IC50 = 10 nM); inhibits VEGFR2 (IC50 = 140 nM); selectively inhibits PDGF- over VEFG-, FGF-, and EGF-induced cell proliferation (IC50s = 0.11, 10, 10, and 21.9 μM, respectively); accelerates downregulation of fibroblast genes and increases the yield of beating clusters in HFFs treated with 15 compounds to induce a cardiac myocyte-like phenotype