Z-Leu-Leu-Leu-B(OH)2 is a proteasome inhibitor with diverse biological activities.{49657,49658,49659} It inhibits LPS-induced expression of FMS-related tyrosine kinase 1 (FLT1) in isolated human microvascular endothelial cells and macrophages.{49657} Z-
英文名:
MG 262
库存:
1 mg, 200 µg
供应商:
Cayman
CAS号:
179324-22-2
A proteasome inhibitor with diverse biological activities; inhibits LPS-induced expression of FLT1 in isolated human microvascular endothelial cells and macrophages; reduces heat shock-induced increases in Hsp70 levels in neonatal rat cardiomyocytes at 1 µM; induces accumulation of the UbG76V-GFP reporter in and apoptosis of growth plate chondrocytes, as well as growth retardation in mice at 1 µmol/kg