Akt inhibitor VIII is a potent allosteric inhibitor of Akt1 and Akt2 (IC50s = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 µM).{24205,24204,24208} It is a poor or ineffective inhibitor of a wide range of other seri
库存:
1 mg, 10 mg, 5 mg, 500 µg
供应商:
Cayman
CAS号:
612847-09-3
规格:
This biochemical is available in the following size(s) 100 mg, 25 mg, 50 mg - Please inquire
A potent, allosteric inhibitor of Akt1 and Akt2 (IC50 = 58 and 210 nM, respectively) that less effectively blocks Akt3 activity (IC50 = 2.2 µM); cell permeable, blocking insulin regulation of FOXO1 activity at 1 µM in rat hepatoma cells