Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP (Item No. 17144) and cyclic di-AMP (Item No. 17753).{34773} C-di-IMP has adjuvant properties when co-administer
英文名:
c-di-IMP|Cyclic di-inosine monophosphate
库存:
1 mg, 500 µg
供应商:
Cayman
A synthetic second messenger; has mucosal adjuvant properties in vitro and in vivo by the mucosal route; enriches the population of MHC class I and II, CD80, CD86, CD40, and CD54 positive dendritic cells derived from murine bone marrow; stimulates macrophages at 200 ng/ml; intranasal immunization with β-gal increases IgG titers up to 2-fold and induces a Th1/Th2 response