Pifithrin-α (PFT-α; Item No. 13326) is a reversible inhibitor of p53-dependent transcription and apoptosis.{17259} Cyclic PFT-α, also known as PFT-β, is a stable analog of PFT-α, formed by the condensation of pifithrin-α in solution.{23585} It inhibits t
英文名:
Cyclic PFT-α|PFT-β|Pifithrin-β
库存:
10 mg, 25 mg, 5 mg, 50 mg
供应商:
Cayman
CAS号:
511296-88-1
A stable analog of PFT-α, formed by the condensation of PFT-α in solution; inhibits the growth of the cancer cell lines IGROV-1, A2780, and HCT116 (IC50 = 23, 77, and 103 μM, respectively); induces autophagy in HCT116 cells and sensitizes IGROV-1 and H460 cells to anti-microtubule agents