MK-3102 is an inhibitor of dipeptidyl peptidase 4 (DPP-4; IC50 = 1.6 nM).{37137} It is selective for DPP-4 over several proteases, including DPP-7, DPP-8, DPP-9, and fibroblast activation protein (FAP; IC50s = >67 µM for all), as well as the ion channel
英文名:
Omarigliptin
库存:
1 mg, 10 mg, 25 mg, 5 mg
供应商:
Cayman
CAS号:
1226781-44-7
A DPP-4 inhibitor (IC50 = 1.6 nM); selective for DPP-4 over several proteases, including DPP-7, DPP-8, DPP-9, and FAP (IC50s = >67 µM for all), as well as the ion channels Ikr, Cav1.2, Nav1.5 (IC50 = >30 µM for all) and a panel of 168 enzymes (IC50s = >10 µM for all); reduces blood glucose levels by 51% in mice at 0.3 mg/kg