X-Linked inhibitor of apoptosis (XIAP) is a protein which modulates several pathways, including several related to apoptosis.{21506} Embelin is a natural benzoquinone, isolated from plants of the genus Embelia, which directly binds and inhibits XIAP (IC5
英文名:
NSC 91874
库存:
10 mg, 100 mg, 50 mg
供应商:
Cayman
CAS号:
550-24-3
规格:
This biochemical is available in the following size(s) 100 mg, 25 mg, 50 mg - Please inquire
A natural benzoquinone which directly binds and inhibits XIAP (IC50 = 4.1 μM); blocks growth while activating caspases and promoting apoptosis in cancer cells expressing high levels of XIAP; prevents NF-κB activation by inhibiting IKK; protects against XIAP- and caspase-dependent inflammation