Matreya,LLC是一家油脂生化公司,提供综合系列的鞘脂、糖脂、神经节苷脂、球三糖神经酰胺、脂肪酸和甾醇。我们在高纯度产品和专门的技术援助方面享有可靠的声誉。 Matreya致力于开发和制造的脂质和生化物质。我们提供高质量的化学合成和天然产物的提取和纯化。惠诚生物把Matreya已经引入到国内市场,大量现货销售及产品服务。 This product is a well-defined sulfatide containing an octadecanoyl group acylated to the amine of the sphingosine and is ideal as an internal standard. Sulfatide is a type of sulfolipid that is found primarily in the central nervous system and is a myelin-specific sphingolipid. A deficiency of sulfatide in white and gray matter has been associated with Alzheimer’s disease and other types of dementia. Apoliprotein E plays an important regulating role in the metabolism of sulfatides.1 The production of anti-sulfatide antibodies in the cerebrospinal fluid, leading to a deficiency in sulfatides, may be a cause of degeneration of the myelin sheath, leading to multiple sclerosis and other demyelinating diseases.2 Metachromatic leukodystrophy is an inherited disorder characterized by a deficiency of the lysosomal enzyme arylsulfatase A and the subsequent accumulation of sulfatide in neural and visceral tissues.3 Sulfatide also regulates the differentiation of oligodendroblasts. Central nervous system (CNS) myelin is strongly inhibitory to growing axons and sulfatides present in the myelin of the CNS have been identified as major myelin-associated axon growth inhibitors.4 A low level of serum sulfatides has been linked with an increased risk of cardiovascular disease in some situations. Sulfatides in the myelin, especially cistetracosenoyl- sulfatides, stimulate a distinct population of CD1d-restricted natural killer T cells giving these sulfatides important implications for the design of therapeutics that target T cells reactive for myelin glycolipids in autoimmune diseases of the central nervous system.5上海惠诚生物专业优势供应Matreya磷脂类标准品 ,每周三和国外下单,2周到货。更多关于Matreya品牌脂类标准品,欢迎拨打惠诚生物客户服务电话021-60498804