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鼠gamma H2AX 单克隆抗体
- 参考价格： 询价
- 品 牌： novus
- 货 号： NBP1-19255
- 靶 点： gamma H2AX 查看全部gamma H2AX 抗体
- 适应物种： 人,小鼠,大鼠,牛,犬,鸡,豚鼠,猪,灵长类动物,兔,绵羊
- 应用范围： 免疫印迹
- 克 隆 性： Monoclonal
- 宿 主： Mouse
产品概览
| 背景： | H2A.X is a member of the histone H2A family, 1 of 5 families of histone proteins involved in nucleosomal organization of chromatin. H2A.X is synthesised in G1 as well as S phase and is known to be important for recombination between immunoglobulin switch regions. A very early step in the response of mammalian cells to DNA double-strand breaks is the phosphorylation of histone H2A.X at serine 139 at the sites of DNA damage. There is a predicted acetylation at residue 1 and ubiquitination at reside 119. Phosphorylated H2A.X promotes DNA repair and maintains genomic stability. |
| 免疫原： | Synthetic phospho-peptide derived from the sequence of human Histone H2AX phosphorylated at Ser139. |
| 产品保证说明： | All of our products are backed by our 100% guarantee to work for stated and predicted species and applications. |
| 产品别名： | H2A/XH2a/xH2A.XH2AXhistone H2A.xH2AX histoneH2A histone family, member X |
| 克隆： | 9F3 |
产品特性
| 纯度： | Protein G purified |
靶点信息
| uniprot： |
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| 基因： | H2AFX |
| 基因标志： | H2AFX |
| 基因相关产品： | ATM,TP53,CHEK2,TP53BP1,GAMMAH2AX,CHEK1,ATR,CDKN1A,MMAB,ANTXR1,NBN,MRE11A,PARP1,MDC1,DDR1,BRCA1,PRKDC,TCEAL1,NSG1,CASP3 |
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| uniprot： |
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应用与保存
| 免疫原： | Synthetic phospho-peptide derived from the sequence of human Histone H2AX phosphorylated at Ser139. |
| 防腐剂： | 0.09% Sodium Azide |
| 应用说明： | Detects a band of ~16kDa by Western blot. |
| 稀释浓度： |
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其他
| 保存条件： | Store at -20C. Avoid freeze-thaw cycles. |
| 分子量： | 15 kDa |
| 备注： | Licensed to Novus Biologicals LLC under U.S. Patent Nos. 6,362,317 and 6,884,873. |
| 标记： | DNA Double-strand break marker |
| 浓度： | Please see the vial label for concentration. If unlisted please contact technical services. |
| 温馨提示： | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies areguaranteedfor 1 year from date of receipt. |
| 缓冲液： | PBS; pH 7.2 and 50% glycerol. |
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