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抗人cyp7b1多克隆抗体
- 参考价格： ¥1100.0 - 2600.0
- 品 牌： abgent
- 货 号： AP8786c
- 适应物种： 人
- 应用范围： 免疫印迹,免疫组化,流式细胞技术,免疫荧光
- 克 隆 性： 多克隆
- 亚 型： Rabbit Ig
- 抗体类型： 一抗
产品概览
| 背景： | CYP7B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.REFERENCESSchwarz,M., et.al., Curr. Opin. Lipidol. 9 (2), 113-118 (1998) |
| 其他名字： | CYP7B1; 25-hydroxycholesterol 7-alpha-hydroxylase; Cytochrome P450 7B1; Oxysterol 7-alpha-hydroxylase |
靶点信息
| 基因id： | 9420 |
| 蛋白名： | CYP7B1 |
| 胞内定位： | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein |
应用与保存
| 稀释浓度： | WB~~1:1000WB~~1:1000IHC~~1:50~100FC~~1:10~50IF~~1:10~50 |
| 注意事项： | CYP7B1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
其他
| 参考文献： | Schwarz,M., et.al., Curr. Opin. Lipidol. 9 (2), 113-118 (1998) |
| 保存条件： | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| 标记物： | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| 主要序列号： | O75881 |
| 分子量： | 58256 Da |
| 规格： | 80 µl (8 western blots) | 价格： | ¥1100.00 |
| 规格： | 400 µl (40 western blots) | 价格： | ¥2600.00 |
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