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DESCRIPTION: Caspase-9 is an initiator caspase, encoded by the CASP9 gene. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3, proteolytically cleaves poly(ADP-ribose) polymerase (PARP). The caspase 9 antibody aiso has alternative names which are APAF 3 antibody, Apoptosis related cysteine peptidase antibody, Apoptotic protease-activating factor 3 antibody and CASP 9 antibody SPECIES REACRIVITY: Human,Mouse,Rabbit ISOTYPE: IgG1 PRODUCE TYPE: Primary Antibody TESTED APPLICATIONS: WB APPLICATIONS: WB: 1:1,000-5,000 *NOTE: Optimal working dilutions must be determined by the end user ANTIBODY TYPE: Monoclonal Antibody MOLECULAR WEIGHT: 47kDa (Human) 51kDa (Rabbit, Mouse) STORAGE/CONDITION: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Store at -20°C. Do not aliquot the antibody. For research use only; not for use as a diagnostic. Important Note: During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200 µL or less, we recommend gently dislodge any liquid in the container,‘s cap. |