Dengue virus (DENV) is a single-stranded RNA virus belonging to flavivirus family. There are 4 serotypes of the virus (called DEN-1, -2, -3 and -4) have been found. The DENV genome encodes 3 structural (capsid C, membrane M, and envelope E) and 7 nonstructural (NS1, NS2A, NS2B, NS3, NS4A, NS4B, and NS5) proteins. arigo offers quality antibodies against structural and nonstructural proteins of Dengue virus.
◆ DENV-Specific No cross reactivity with Zika virus. ◆ Multiple Applications Good for use in ELISA, WB, ICC, IHC, FACS. ◆ High Consistency Mouse monoclonal antibodies ensure consistency and reproducibility. |
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Easy-to-use ELISA kits for diagnostic testing of DENV-infection |
Laboratory diagnosis of dengue virus infection includes detection of viral RNA, antigen, or antibodies. The NS1 antigen can be detected as early as 1 day post onset of symptoms. The IgM/IgG antibody ratios are commonly used to distinguish primary and secondary infection. arigo offers easy-to-use ELISA kits to facilitate early diagnosis and discrimination between primary and secondary infection. |
Benefits ● Early: NS1 is detectable on day 1 post onset. ● Easy: Only a single dilution of serum required. ● Fast: ~2.5 hr assay time. ● Flexible: Plasma, serum, and culture sup. can be used. ● Reliable: Detection of all 4 DENV serotypes ● Specific: No cross-reactivity with Zika virus. ● Citation: Sanaki et al., (2019) FASEB J. 33(12):13866-13881. |
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IgM / IgG antibody ratios are commonly used to distinguish primary and secondary infection. Primary infection patients have a higher IgM/IgG ratio while IgG levels are typically higher in the secondary infection stage. |
Benefits ● Fast: ~2 hr assay time. ● Flexible: Plasma and serum can be used ● Optimal: Only 10 µl sample required. |
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