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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
139339-45-0
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥2750.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥1136.0 |
| 规格: | 5 mg | 产品价格: | ¥2500.0 |
| 规格: | 10 mg | 产品价格: | ¥3800.0 |
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Ro24-7429
CAS No. : 139339-45-0
MCE 国际站:Ro24-7429
产品活性:Ro24-7429 是一种有效且具有口服活性的 HIV-1 反式激活蛋白 Tat 拮抗剂。Ro24-7429 也是 RUNX1 抑制剂。Ro24-7429 具有抗 HIV、抗纤维化和抗炎作用。
研究领域:Anti-infection | Apoptosis
In Vitro: Ro 24-7429 (0.1-5 μM; 3 days) induces apoptosis of cultured PBMCs in a dose-dependent manner.
Ro 24-7429 (1-25 μM) also induces apoptosis and inhibits antigen-induced lymphocyte proliferation.
Ro24-7429 (50-200 μM; 24-72 hours) strongly inhibits the proliferation of A549 and HLF cells in a dose-dependent manner. Ro24-7429 treatment (75 μM) significantly reduces TNF-α-induced up-regulation of RUNX1 mRNA by 50% at 48 hours.
In Vivo: Ro24-7429 (17.5-70 mg/kg; i.p.; daily; for 14 or 21 days) treatment robustly ameliorates lung fibrosis and inflammation in the Bleomycin-induced pulmonary fibrosis (PF) mouse model. Ro24-7429 curbs expression of fibrosis markers in injured mouse lungs.
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文献和实验4.3.1 真菌 最近,多数转基因小麦和大麦的田间试验涉及抗真菌研究(表 20. 1 和表 20.2)。 其中一个申请项目来自先正达公司,它们申请在加拿大马的尼托巴种植抗镰刀菌的材料 ( 申请号 06-sbil-295 - wht01-0871-mb007-01) 。其他已报道的研究还包括提高综合抗性[24]、抗网腫黑稿病 (TriZeiia caries) [ 25]、抗白粉病(Blumeria grominis) [26,27 ] 、抗赤霉病 ( gramineamm ) [
CD1-CD8、CD27、CD28、CD38、CD39、CDw60、CD45、CD45RA、CD45RB、CD45RO、CD98、CD99、CD99R、CD100、CDw101 B细胞 CD10、CD19-CD24、CD37、CD40、CD53、CD72-CD75、CDw76、CD77、CD78、CD79a、CD79b、CD80-CD83、CDw84、CD85、CD
Biological coating procedures for glass coverslips
1. Dissolve 100 mg gelatin in 100 ml water (triple glass distilled or RO). 2. Autoclave to sterilize. 3. While hot, thoroughly mix gelatin solution. 4. Add enough solution to pool over surface of sterile glass coverslip. 5. Chill for 2-24 hours
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