- ￥450 - 5724
- MedChemExpress(MCE)
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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
GBL-5g
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
646530-37-2
- 规格：
1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 1 mg | 产品价格： | ￥450.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥1072.0 |
| 规格： | 10 mg | 产品价格： | ￥1668.0 |
| 规格： | 25 mg | 产品价格： | ￥2880.0 |
| 规格： | 50 mg | 产品价格： | ￥4080.0 |
| 规格： | 100 mg | 产品价格： | ￥5724.0 |
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UTL-5g
CAS No. : 646530-37-2
MCE 国际站：UTL-5g
产品活性：UTL-5g (GBL-5g) 是一种抗炎性 TNF-α 抑制剂，具有化学保护和肝脏放射保护作用。UTL-5g 通过抑制 TNF-α 等因子降低顺铂引起的肝毒性、肾毒性和骨髓毒性。
研究领域：Apoptosis
作用靶点：TNF Receptor
In Vitro: RAW 264.7 macrophages are transfected with the respective reporter assay plasmids, pretreated with UTL-5g at 1, 10 or 50 µM for 60 min and then challenged with 100 ng/ml LPS. After a 16 h incubation, transcription factor activity is measured. Transcription factors that shows a UTL-5g dose-dependent decrease in activity in two experiments are categorized as being disrupted by UTL-5g.
In Vivo: UTL-5g (GBL-5g) lowers levels of TGF-β and TNF-α elevated by lung irradiation.
UTL-5g (60 mg/kg; p.o.; daily for 4 days) shows positive effects in increasing the survival rates and extending the survival times.
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文献和实验, incubate for 30 min at 37°C. ( 5g powdered milk in 95 ml PBS)5 Rinse with PBS 3x.6 Add 50 µl of antibody, incubate 30 min at 37°C.7 Rinse with PBS 3x.8 Add 50 µl of goat anti-mouse IgG conjugate with alkaline phosphatase.(1 µl of conjugate in 4 ml of PBS
1．Vogel-Bonner液10×（VB液10倍浓缩）用于配制底层基本培养基。配制方法：硫酸镁（MgSO 4 ·7H 2 O）1g，柠檬酸（C 6 H 8 O 7 ·H 2 O）10g，磷酸氢二钾（K 2 HPO 4 ·3H 2 O）65.5g，磷酸氢铵钠（NaNH 4 HPO 4 ·4H 2 O
CHROME GELATINISED SLIDES AND COVERSLIPS
Dissolve 5g of gelatine in 1 litre of distilled water. Do not heat over 60C. When the gelatine has dissolved add 0.5g of chrome alum (chromic potassium sulphate). Cool and dip racks of slides
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