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文献和实验In Vitro Drug Metabolism: Thiol Conjugation
extraction of the reaction mixture. The resulting samples are subject to reversed-phase chromatography. Further on-line detection and identification of thiol conjugates by mass spectrometry are performed in a stepwise manner from neutral loss and/or parent
Reversible Covalent Immobilization of Enzymes Via Their Thiol Groups
This enzyme immobilization approach involves the formation of disulfide (S-S) bonds with the support. Thus, enzymes bearing exposed nonessential thiol (SH) groups can be immobilized onto thiol-reactive supports provided with reactive
Fabrication and Characterization of Bioactive Thiol-Silicate Nanoparticles
Here we describe a new method for the production of thiol-silicate particles and the entrapment of enzymes within the thiol particles as they are formed. When bio-inspired polymers (polyethyleneimine) are combined with a silicic acid source
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