交叉反应 |
Human, Mouse, (predicted: Rat, Chicken, Dog, Pig, Cow, Rabbit, ) |
产品介绍 |
Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleous. Function: Involved with pre-mRNA processing. Forms complexes (ribonucleosomes) with at least 20 other different hnRNP and heterogeneous nuclear RNA in the nucleus. Subunit: Identified in the spliceosome C complex. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with IGF2BP1. Subcellular Location: Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Predominantly nucleoplasmic, however isoform A2 is also found in the cytoplasm of cells in some tissues Similarity: Contains 2 RRM (RNA recognition motif) domains. SWISS: P22626 Gene ID: 3181 Database links: Entrez Gene: 3181 Human Entrez Gene: 100045191 Mouse Entrez Gene: 53379 Mouse Entrez Gene: 362361 Rat Omim: 600124 Human SwissProt: P22626 Human SwissProt: O88569 Mouse SwissProt: A7VJC2 Rat Unigene: 487774 Human Unigene: 155896 Mouse Unigene: 4057 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |