英文名称phospho-GCN2 (Thr667)中文名称磷酸化蛋白激酶GCN2蛋白抗体别 名GCN2 (phospho T667); p-GCN2 (phospho T667); EIF2AK4; Eukaryotic Translation Initiation Factor 2-alpha kinase 4; GCN2-like protein; KIAA1338; E2AK4_HUMAN; Eif2ak4; Eukaryotic Translation Initiation Factor 2 alpha kinase 4; GCN2; GCN2 eIF2alpha kinase; GCN2-like protein; MGCN2. 产品类型磷酸化抗体 研究领域细胞生物 神经生物学 抗体来源Rabbit克隆类型Polyclonal交叉反应Mouse, Rat, (predicted: Human, Dog, Cow, Horse, )产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.分 子 量181kDa细胞定位细胞浆 性 状Liquid浓 度1mg/ml免 疫 原KLH conjugated Synthesised phosphopeptide derived from human GCN2 around the phosphorylation site of Thr667:PG(p-T)PP 亚 型IgG纯化方法affinity purified by Protein A储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.PubMedPubMed产品介绍GCN2 belongs to a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor 2 to downregulate protein synthesis in response to varied cellular stresses.
Tissue Specificity:
Widely expressed.
Post-translational modifications:
Autophosphorylated on threonine residues.
Similarity:
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.
Contains 2 protein kinase domains.
Contains 1 RWD domain.