CRISPLD1; CocoaCrisp; CRISP 10; CRISP-10; CRISP10; CRISPLD 1; Crispld1; CRLD1_HUMAN; Cysteine rich secretory protein 10; Cysteine rich secretory protein LCCL domain containing 1; Cysteine-rich secretory protein 10; Cysteine-rich secretory protein LCCL domain-containing 1; LCCL domain containing cysteine rich secretory protein 1; LCCL domain-containing cysteine-rich secretory protein 1; LCRISP1; Trypsin inhibitor Hl; UNQ342/PRO541.
研究领域
细胞生物 信号转导 转录调节因子
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, )
产品应用
WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蜡切片需做抗原修复) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
54kDa
细胞定位
细胞浆
性 状
Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human CRISP10:301-400/500
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Cysteine-rich secretory proteins (CRISPs) represent a family of evolutionarily conserved proteins which may play a role in the innate immune system and are transcriptionally regulated by androgens in several tissues. CRISP proteins are highly expressed in the mammalian reproductive tract and in the venom secretory ducts of some reptiles. CRISP-10 (cysteine-rich secretory protein 10), also known as CocoaCrisp and Trypsin inhibitor Hl, is a 500 amino acid protein containing 2 LCCL domains, which are thought to function as autonomous folding domains used to construct modular proteins through exon shuffling. CRISP-10 differs from other CRISP proteins in that it does not contain the 10 conserved cysteine residues or ICR domains that are usually conserved throughout the CRISP family.
Subcellular Location: Secreted.
Similarity: Belongs to the CRISP family. Contains 2 LCCL domains.