细胞角蛋白5+6抗体

英文名称CK5+CK6中文名称细胞角蛋白5+6抗体别    名CK5+6; Cytokeratin 5 + 6; Cytokeratin 5; Keratin, type II cytoskeletal 5; CK-5; Keratin-5; K5; 58 kDa cytokeratin; KRT5; CK 5; DDD; EBS 2; EBS2; K5; Keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); Keratin 5; Keratin Type II Cytoskeletal 5; Keratin5; KRT 5; KRT 5A; KRT5.KRT6A; CK6A; CK6B; CK6C; CK6D; CK 6E; K6A; K6C; K6D; KRT6C; Cytokeratin 6a; Cytokeratin 6B; Cytokeratin 6C; Cytokeratin 6D; Cytokeratin 6E; Cytokeratin6; k6a keratin; K6B; K6b keratin; K6c keratin; K6d keratin; K6e keratin; k6hf; Keratin 6 isoform K6e; Keratin 6C; Keratin 6E; Keratin K6h; Keratin type II cytoskeletal 6A; Keratin type II cytoskeletal 6B; Keratin type II cytoskeletal 6C; Keratin type II cytoskeletal 6D; Keratin type II cytoskeletal 6E; KRT6; KRT6A; KRT6B; KRT6C; KRT6D; KRT6E; MGC102925.  研究领域肿瘤  抗体来源Rabbit克隆类型Polyclonal交叉反应Human, Mouse, 产品应用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1μg/Test ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.分 子 量62/60kDa细胞定位细胞核 细胞浆 细胞膜 性    状Liquid浓    度1mg/ml免 疫 原KLH conjugated synthetic peptide derived from human CK5+CK6:161-220/590 亚    型IgG纯化方法affinity purified by Protein A储 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.PubMedPubMed产品介绍Keratins 5, 6 are members of type II keratins family that are specifically expressed in the inner root sheath of hair follicles. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Keratin 18 is memeber of the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family.

SWISS:
P02538

Gene ID:
3852

Database links:

Entrez Gene: 3852 Human

Entrez Gene: 3853 Human

Entrez Gene: 3854 Human

Omim: 148040 Human

SwissProt: P02538 Human

SwissProt: P04259 Human

SwissProt: P13647 Human

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

细胞角蛋白5&6是高分子量细胞角蛋白，分子量分别为58KDa和56KDa。其表达在皮肤的基底细胞、棘层细胞和部分前列腺基底细胞。主要用于间皮瘤和腺癌的鉴别诊断，并可辅助诊断前列腺良恶性病变。