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- 详细信息
- 文献和实验
- 技术资料
- 英文名：
vero E6
- 库存：
1x10^6/瓶
- 供应商：
上海酶研
- 肿瘤类型：
详询
- 细胞类型：
vero E6
- 品系：
vero E6
- 组织来源：
非洲绿猴肾细胞
- 相关疾病：
详询
- 物种来源：
非洲绿猴
- 免疫类型：
详询
- 细胞形态：
贴壁/悬浮
- 是否是肿瘤细胞：
否
- 器官来源：
非洲绿猴肾细胞
- 运输方式：
顺丰快递
- 年限：
5年
- 生长状态：
生长良好
- 规格：
瓶
vero E6、vero E6、vero E6细胞、vero E6细胞、vero E6非洲绿猴肾细胞
Cell line name Vero C1008
Synonyms VERO C1008; VeroC1008; VEROC1008; VERO C 1008; VERO C1008 (E6); Vero 76 clone E6; Vero 76 clone E-6; Vero E-6; Vero E6; VERO E6; Vero-E6; VeroE6
Accession CVCL_0574
Resource Identification Initiative To cite this cell line use: Vero C1008 (RRID:CVCL_0574)
Comments Group: Non-human primate cell line.
Group: Vaccine production cell line.
Virology: Susceptible to infection by many viruses. Supports the growth of slowly replicating viruses (ATCC=CRL-1586).
Virology: Susceptible to infection by SARS coronavirus (SARS-CoV). Produces a lytic infection (PubMed=15731278; PubMed=16494729).
Virology: Susceptible to infection by SARS coronavirus 2 (SARS-CoV-2) (COVID-19) (PubMed=32020029; PubMed=32511316; PubMed=33389257; PubMed=34339474).
Doubling time: 22 hours (ATCC=CRL-1586).
Derived from site: In situ; Kidney, epithelium; UBERON=UBERON_0004819.
Cell type: Epithelial cell of kidney; CL=CL_0002518.
Species of origin Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus) (NCBI Taxonomy: 60711)
Hierarchy Parent: CVCL_0603 (Vero 76)
Children:
CVCL_D7CA (Abeomics Vero ACE2) CVCL_D7CB (Abeomics Vero GFP) CVCL_JX48 (sVero p66)
CVCL_E1F0 (Ubigene Vero E6 ATG7 KO) CVCL_E1F1 (Ubigene Vero E6 GSDME KO) CVCL_E1F2 (Ubigene Vero E6 PIK3C3 KO)
CVCL_E1F4 (Ubigene Vero E6 STAT1 KO) CVCL_E1F6 (Ubigene Vero E6 ZDHHC20 KO) CVCL_A7UJ (Vero E6-high ACE2)
CVCL_XD71 (Vero E6-S) CVCL_C7NK (Vero E6-TMPRSS2-T2A-ACE2) CVCL_YZ66 (Vero E6/NPC1-KO cl.19)
CVCL_C4RQ (VeroE6-Pgp-KO) CVCL_YQ49 (VeroE6/TMPRSS2)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications
CLPUB00328
Earley E.M., Johnson K.M.
The lineage of Vero, Vero 76 and its clone C1008 in the United States.
(In book chapter) Vero cells: origin, properties and biomedical applications; Simizu B., Terasima T. (eds.); pp.26-29; Department of Microbiology, School of Medicine, Chiba University; Chiba; Japan (1988)
PubMed=15731278; DOI=10.1128/JVI.79.6.3846-3850.2005; PMCID=PMC1075706
Mossel E.C., Huang C., Narayanan K., Makino S., Tesh R.B., Peters C.J.
Exogenous ACE2 expression allows refractory cell lines to supportplication.
J. Virol. 79:3846-3850(2005)
PubMed=16494729; DOI=10.3201/eid1201.050496; PMCID=PMC3291385
Kaye M., Druce J., Tran T., Kostecki R., Chibo D., Morris J., Catton M., Birch C.
SARS-associated coronavirus replication in cell lines.
Emerg. Infect. Dis. 12:128-133(2006)
PubMed=19016439; DOI=10.1002/9780471729259.mca04es11; PMCID=PMC2657228
Ammerman N.C., Beier-Sexton M., Azad A.F.
Growth and maintenance of Vero cell lines.
Curr. Protoc. Microbiol. 11:A.4E.1-A.4E.7(2008)
PubMed=32020029; DOI=10.1038/s41422-020-0282-0; PMCID=PMC7054408
Wang M.-L., Cao R.-Y., Zhang L.-K., Yang X.-L., Liu J., Xu M.-Y., Shi Z.-L., Hu Z.-H., Zhong W., Xiao G.-F.
Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro.
Cell Res. 30:269-271(2020)
PubMed=32511316; DOI=10.1101/2020.03.02.972935; PMCID=PMC7239045
Harcourt J.L., Tamin A., Lu X.-Y., Kamili S., Kumar-Sakthivel S., Murray J., Queen K., Tao Y., Paden C.R., Zhang J., Li Y., Uehara A., Wang H.-B., Goldsmith C., Bullock H.A., Wang L.-J., Whitaker B., Lynch B., Gautam R., Schindewolf C., Lokugamage K.G., Scharton D., Plante J.A., Mirchandani D., Widen S.G., Narayanan K., Makino S., Ksiazek T.G., Plante K.S., Weaver S.C., Lindstrom S., Tong S.-X., Menachery V.D., Thornburg N.J.
Isolation and characterization of SARS-CoV-2 from the first US COVID-19 patient.
bioRxiv 2020:972935-972935(2020)
PubMed=33389257; DOI=10.1007/s10096-020-04106-0; PMCID=PMC7778494
Wurtz N., Penant G., Jardot P., Duclos N., La Scola B.
Culture of SARS-CoV-2 in a panel of laboratory cell lines, permissivity, and differences in growth profile.
Eur. J. Clin. Microbiol. Infect. Dis. 40:477-484(2021)
PubMed=34339474; DOI=10.1371/journal.pone.0255622; PMCID=PMC8328321
Pommerenke C., Rand U., Uphoff C.C., Nagel S., Zaborski M., Hauer V., Kaufmann M., Meyer C., Denkmann S.A., Riese P., Eschke K., Kim Y., Safranko Z.M., Kurolt I.-C., Markotic A., Cicin-Sain L., Steenpass L.
Identification of cell lines CL-14, CL-40 and CAL-51 as suitable models for SARS-CoV-2 infection studies.
PLoS ONE 16:E0255622-E0255622(2021)
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文献和实验*发表【中文论文】请标注：由上海酶研生物科技有限公司提供；
*发表【英文论文】请标注：From Shanghai EK-Bioscience Biotechnology Co., Ltd.
技术资料