- ￥4400
- Matreya, LLC
- 美国
- M-1047
- 2025年08月21日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
-20
- 保质期：
见产品包装
- 英文名：
Phosphatidylserine
- 库存：
99
- 供应商：
齐源生物
- CAS号：
51446-62-9
- 规格：
1 ml (50 mg/ml)
CAS号：51446-62-9
规格：1 ml (50 mg/ml)
纯度：≥98%
品牌：Matreya, LLC
货号：M-1047
分子量：788
分子式：C42H78NO10P (oleoyl)
保存温度：-20
Sales class ：Normal
Formulation ：A neat liquid
Item Synonyms ：PS
Item origin ：Animal/Bovine
Availability status：Worldwide
Application Notes：Phosphatidylserine (PS) is a negatively charged glycerophospholipid that is widespread but quantitatively minor phospholipid in mammalian cells. PS is found mainly in animals and white beans. PS is found mostly on the inner layer of the plasma membrane. During cell apoptosis it is redistributed to the outer layer where it functions as a ligand for phagocyte recognition and as an anti-inflammatory.1 In vertebrates, PS is a signal for removal by macrophages. PS is also externalized for various cellular functions such as cell fusion, blood clotting and regulating cell signaling. It acts as an important part of the lipid-calcium-phosphate complex needed for mineral formation.2 PS has been extensively investigated for a number of possible therapeutic roles including treating dementia, relieving stress, and recovering from exercise.3
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文献和实验Quantification of Selective Phosphatidylserine Oxidation During Apoptosis
of phospholipid-dependent signaling. Phosphatidylserine (PS), in particular, is implicated in the regulation of macrophage-dependent clearance of apoptotic cell “corpses” in a pathway probably mediated by selective oxidation and translocation of PS in the plasma
In classical, ninhydrin-based amino acid analysis (1 ,2 ), the ion-exchange matrix used for separation becomes contaminated upon consecutive analyzes of extremely lipid-rich samples; in our experience, already after approx 20–30 samples
We present here the application of a novel assay that measures the absolute amount of phosphatidylserine (PS) externalized on the surface of cells. Although the assay is based on the same annexin binding principle as the fluorescent flow
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