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- 详细信息
- 文献和实验
- 技术资料
- 靶点:
SREBP1
- 浓度:
1 mg/mL.
- 应用范围:
WB,IF-Cell,IHC-P
- 宿主:
Rabbit
- 适应物种:
Human,Mouse
- 保质期:
1年
- 供应商:
Huabio
- 标记物:
Non-conjugated
- 保存条件:
Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.
- 形态:
Liquid
- 亚型:
IgG
- 免疫原:
Synthetic peptide within N-terminal human SREBP1 from aa25-aa55.
- 规格:
50μl/100μl
| 规格: | 50μl | 产品价格: | ¥1500.0 |
|---|---|---|---|
| 规格: | 100μl | 产品价格: | ¥2500.0 |
This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively.
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HA500210·Anti-SREBP1 Antibody
¥1500 - 2500




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