关键词:VDAC3抗体;线粒体外膜孔蛋白3抗体;线粒体外膜孔蛋白3;Voltage-dependent anion-selective channel protein 3; VDAC-3; hVDAC3; Outer mitochondrial membrane protein porin 3;ABP60884
VDAC3 (Voltage Dependent Anion Channel 3) is a Protein Coding gene. Among its related pathways are Calcium signaling pathway and Deubiquitination. VDAC3 encodes a voltage-dependent anion channel (VDAC, and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for VDAC3.