MAP4K1 is a Protein Coding gene. Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1 is a serine/threonine-protein kinase, which may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. May play a role in hematopoietic lineage decisions and growth regulation. Able to autophosphorylate. Among its related pathways are Prostate Cancer and B Cell Receptor Signaling Pathway (WikiPathways). Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MAP4K3.