- ￥360 - 5136
- MedChemExpress(MCE)
- 美国
- HY-15307A
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture
- 英文名：
KD025 mesylate; SLx-2119 mesylate
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
2109704-99-4
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥1014.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥360.0 |
| 规格： | 5 mg | 产品价格： | ￥840.0 |
| 规格： | 10 mg | 产品价格： | ￥1140.0 |
| 规格： | 25 mg | 产品价格： | ￥2020.0 |
| 规格： | 50 mg | 产品价格： | ￥3480.0 |
| 规格： | 100 mg | 产品价格： | ￥5136.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
Belumosudil mesylate
CAS No. : 2109704-99-4
MCE 国际站：Belumosudil mesylate
产品活性：Belumosudil mesylate (KD025 mesylate) 是一种选择性的 ROCK2 抑制剂，对 ROCK2 和 ROCK1 的 IC50 值分别为 105 nM 和 24 µM。具有抗纤维化特性。
研究领域：Cell Cycle/DNA Damage | Stem Cell/Wnt | Cytoskeleton | TGF-beta/Smad
作用靶点：ROCK
In Vitro: Belumosudil (SLx-2119; 40 µM) induces significant down-regulations of Tsp-1 and CTGF mRNA levels in PASMC. The microarray hybridized with aRNA from HMVEC treated with Belumosudil, shows a 5-times higher background than the other arrays.
In Vivo: Belumosudil (KD-025; 100, 200 or 300 mg/kg, i.p.) dose-dependently reduces infarct volume after transient middle cerebral artery occlusion. Belumosudil is at least as efficacious in aged, diabetic or female mice, as in normal adult males.
相关产品：Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | FDA-Approved Drug Library Mini | Bioactive Compound Library Plus | Cell Cycle/DNA Damage Compound Library | Immunology/Inflammation Compound Library | Kinase Inhibitor Library | Stem Cell Signaling Compound Library | TGF-beta/Smad Compound Library | FDA-Approved Drug Library | Anti-Cancer Compound Library | Anti-Aging Compound Library | Drug Repurposing Compound Library | Reprogramming Compound Library | Anti-diabetic Compound Library | Cytoskeleton Compound Library | FDA Approved & Pharmacopeial Drug Library | Rare Diseases Drug Library | FDA-Approved Anticancer Drug Library | Human Metabolite Library | Anti-Pulmonary Fibrosis Compound Library | Cancer Stem Cells Compound Library | Heterocyclic Compound Library | Membrane Protein-targeted Compound Library | Highly Selective Inhibitors Library | Serine/Threonine Kinase Inhibitor Library | Y-27632 dihydrochloride | Chroman 1 | Belumosudil | Fasudil Hydrochloride | Thiazovivin | Narciclasine | Afuresertib | H-1152 dihydrochloride | GSK269962A | GSK429286A | Ripasudil | CCG-222740 | AT13148 | Y-33075 | LX7101 | HA-100 | GSK180736A | RKI-1447 | ROCK inhibitor-2 | SAR407899 | SR-3677 | Pentanoic acid | Verosudil | BDP5290 | CRT0066854 | Hydroxyfasudil
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
