- ￥2045 - 4950
- MedChemExpress(MCE)
- 美国
- HY-136531
- 2025年12月05日
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- 规格：
10 mM * 1 mL/1 mg/5 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥4950.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥2045.0 |
| 规格： | 5 mg | 产品价格： | ￥4500.0 |
MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。
XMU-MP-3
CAS No. : 2031152-08-4
MCE 国际站：XMU-MP-3
产品活性：XMU-MP-3 是一种有效的非共价 BTK 抑制剂，在 10 μM ATP 存在下，对 BTK WT 和 BTK C481S 突变型的 IC50 分别为 10.7 nM 和 17.0 nM。XMU-MP-3 也诱导凋亡 (apoptosis)。
研究领域：Protein Tyrosine Kinase/RTK | Apoptosis
In Vitro: XMU-MP-3 (0.001-10000 nM; 48 hours) inhibits BTK-transformed Ba/F3 cell proliferation with an IC50 of 11.4 nM.
XMU-MP-3 (1-10000 nM) inhibits the proliferation of JeKo-1, Ramos and NALM-6 with IC50 values of 326.6 nM, 685.6 nM and 1065 nM, respectively.
XMU-MP-3 (0.001-10000 nM) maintains inhibitory potency with an IC50 of 182.3 nM against BTK(C481S)-Ba/F3 cells.
XMU-MP-3 (5000 nM) induces apoptosis in BTK (C481S) Ba/F3 cells.
XMU-MP-3 (10-1000 nM; 4 hours) inhibits both the auto- and trans-phosphorylation of BTK at the site of Y223 and Y551 in a dose-dependent manner in BTK-transformed Ba/F3 cells.
In Vivo: XMU-MP-3 (25 and 50 mg/kg) substantially suppresses tumor growth in mouse xenograft models.
相关产品：Bioactive Compound Library Plus | Apoptosis Compound Library | Kinase Inhibitor Library | Protein Tyrosine Kinase Compound Library | Anti-Cancer Compound Library | Anti-Blood Cancer Compound Library | Membrane Protein-targeted Compound Library | Autoimmune Disease Compound Library | Cell Death Library | MG-132 | Doxorubicin hydrochloride | Bafilomycin A1 | LY294002 | Tamoxifen | Paclitaxel | Y-27632 | Acetylcysteine | Angiotensin II human | 2-Deoxy-D-glucose | Staurosporine | SB-431542 | Actinomycin D | Deferoxamine mesylate | Bortezomib | 5-Fluorouracil | Trametinib | Sorafenib | Oxaliplatin | Gemcitabine | Temozolomide | Rotenone | Mdivi-1 | Elesclomol | Ruxolitinib | Decitabine | SP600125 | MK-2206 dihydrochloride | Etoposide | Monomethyl auristatin E
热门产品线：重组蛋白 | 化合物库 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验-3' +19bs 5'-GCC-GCT-CTA-GAA-CTA-GTG-3' Listing of M13 (pUC) cloning sites As they are read on DNA sequencing gels using the Universal primer: M13mp7 .......EcoR1....BamH1.SalI..PstI..SalI
of a deoxynucleotide base = 324.5 Daltons Average MW of a deoxynucleotide base pair = 649 Daltons 1 ug/ml of DNA = 3.08 uM phosphate 1 ug/ml of 1 kb of DNA = 3.08 nM 5' ends 1 mol of pBR322 = 2.83 x10+6 g. 1 pmol of linear pBR322, 5' ends = 1.4 ug
of a deoxynucleotide base = 324.5 Daltons Average MW of a deoxynucleotide base pair = 649 Daltons 1 ug/ml of DNA = 3.08 uM phosphate 1 ug/ml of 1 kb of DNA = 3.08 nM 5' ends 1 mol of pBR322 = 2.83 x10+6 g. 1 pmol of linear pBR322, 5' ends
技术资料暂无技术资料 索取技术资料
