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- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
1095003-80-7
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥3660.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥1590.0 |
| 规格: | 5 mg | 产品价格: | ¥3500.0 |
| 规格: | 10 mg | 产品价格: | ¥5800.0 |
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p38α inhibitor 2
CAS No. : 1095003-80-7
MCE 国际站:p38α inhibitor 2
产品活性:p38α inhibitor 2 是一种高效选择性 p38α MAPK 抑制剂,pIC50 为 9.6。p38α inhibitor 2 抑制 hERG 离子通道 (IC50=27 μM),在 51 个其他蛋白激酶组 (10 μM 浓度下抑制率 <30%) 和 141 个其他生物靶点组中测试时显示出良好的选择性。
研究领域:MAPK/ERK Pathway
作用靶点:p38 MAPK
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文献和实验-amylases of diverse origin. Three major groups of α-amylase have been characterized, based on molecular weight: 60,000, 24,000, and 12,500 Da. The inhibitor forms a complex with amylase. The complex formation can inactivate the amylase and in turn cause
α2 巨球蛋白(α2 -macroglobulin,α2 MG或AMG)是血浆中分子量最大的蛋白质。分子量约为65.2万-80万,含糖量约8%,由4个亚单位组成。它与淋巴网状系统细胞的发育和功能有密切联系。 α2 MG最突出的特性是能与多种分子和离子结合。特别是它能与不少蛋白水解酶结合而影响这些酶的活性。如与许多肽链内切酶(包括丝氨酸、巯基、羧基蛋白水解酶和一些金属蛋白水解酶)的结合。这些蛋白水解酶有纤维蛋白溶酶、胃蛋白酶、糜蛋白酶、胰蛋白酶及组织蛋白酶D
A Conformationally Restricted -Strand HIV Protease Inhibitor
cyclopropanes as novel [-NH-Cα-] or [-CO-Cα-] bond replacements in pseudopeptides to restrict both side-chain orientation and enforce backbone secondary structures. To test these assumptions, the cyclopropane containing analog 1 (Fig. 1 ) was modeled
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