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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
817635-93-1
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥936.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥400.0 |
| 规格: | 5 mg | 产品价格: | ¥1000.0 |
| 规格: | 10 mg | 产品价格: | ¥1600.0 |
| 规格: | 25 mg | 产品价格: | ¥3350.0 |
| 规格: | 50 mg | 产品价格: | ¥5300.0 |
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PU 23
CAS No. : 817635-93-1
MCE 国际站:PU 23
产品活性:PU 23 是一种多药抗性蛋白 4 (MRP4) 抑制剂,可降低抗肿瘤剂 6-Mercaptopurine 的耐药性。
研究领域:Others
作用靶点:Others
In Vitro: 6-Mercaptopurine (6-MP) inhibits HEK293 and HEK293/MRP4 cells with IC50s of 2.81 and 14.11 μM, respectively. The combination of PU 23 (Cpd23) and 6-Mercaptopurine (6-MP) inhibits HEK293 and HEK293/MRP4 cells with IC50s of 1.84 and 6.06 μM, respectively.
Preincubation of HEK293/MRP4 cells with PU 23 (50 μM) for 2 h also significantly increases the amount of 6-MP in cells.
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文献和实验RNAi Knockdown of Transcription Factor Pu.1 in the Differentiation of Mouse Embryonic Stem Cells
Murine embryonic stem (mES) cells are pluripotent cells derived from the inner cell mass of the preimplantation blastocyst. These cells are primitive and undifferentiated and have the potential to become a wide variety of specialized cell
3.82 3.47 3.25 3.09 2.97 2.87 2.80 2.73 2.64 2.53 2.42 2.31 2.18 2.04 21 22 4.38 3.73 3.44 3.21 3.05 2.93 2.84 2.76 2.70 2.60 2.50 2.39 2.27 2.14 2.00 22 23 4.35 3.75 3.41 3.18 3.02 2.90 2.81 2.73 2.67 2.57 2.47 2.36 2.24 2.11 1.97 23 24
) Cl 17 35.45 铬(chromium) Cr 24 51.99 钴(cobalt) Co 27 58.93
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