7-Chloro-4-(piperazin-1-yl)qui

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7-Chloro-4-(piperazin-1-yl)quinoline

CAS No. : 837-52-5

MCE 国际站：7-Chloro-4-(piperazin-1-yl)quinoline

产品活性：7-Chloro-4-(piperazin-1-yl)quinolone 是活性分子化学中的重要支架。7-Chloro-4-（piperazin-1-yl）quinolone 是有效的 sirtuin 抑制剂，还抑制 5-羟色胺的摄取 (IC₅₀ 为 50 μM)。7-Chloro-4-(piperazin-1-yl)quinolone 对恶性疟原虫 D10 和 K1 菌株表现出抗疟疾活性，IC₅₀ 分别为 1.18 μM 和 0.97 μM。

研究领域：Cell Cycle/DNA Damage  |  Epigenetics  |  Anti-infection

作用靶点：Sirtuin  |  Parasite

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