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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名：
SR1
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1227633-49-9
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg/250 mg/500 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥363.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥165.0 |
| 规格： | 5 mg | 产品价格： | ￥330.0 |
| 规格： | 10 mg | 产品价格： | ￥515.0 |
| 规格： | 25 mg | 产品价格： | ￥1200.0 |
| 规格： | 50 mg | 产品价格： | ￥1989.0 |
| 规格： | 100 mg | 产品价格： | ￥2940.0 |
| 规格： | 250 mg | 产品价格： | ￥4400.0 |
| 规格： | 500 mg | 产品价格： | ￥5725.0 |
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StemRegenin 1
CAS No. : 1227633-49-9
MCE 国际站：StemRegenin 1
产品活性：StemRegenin 1 是一种有效的芳香烃受体 (AhR) 拮抗剂，IC50 为 127 nM。
作用靶点：Aryl Hydrocarbon Receptor
In Vitro: StemRegenin 1 (SR1) acts by antagonizing the aryl hydrocarbon receptor (AhR). StemRegenin 1 increases the number of CD34+ cells after 5 to 7 days with an EC50 of ~120 nM. StemRegenin 1 inhibits photoaffinity ligand (PAL) binding (IC50=40 nM) These results support the conclusion that StemRegenin 1 -induced CD34+ cell expansion is mediated through direct binding and inhibition of the AhR. An aryl hydrocarbon receptor antagonist, StemRegenin 1 (SR1), robustly promotes ex vivo expansion of human CD34+ cells. StemRegenin 1 treatment accelerates the proliferation of CD34+ cells and decreases the expression levels of VentX.
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文献和实验CD49a/CD49b/CD49c/CD49d/CD49e/CD49f分子
CD49a/CD49b/CD49c/CD49d/CD49e/CD49f 分子 CD49a 常用单克隆抗体或代号： SR84,IB3.1;(VLAa 1) 主要表达细胞： Ta,Ba,M [AS] 分子质量(kDa)和结构： gp210,与CD29组成VLA- 1 功 能： 粘附CA和LM CD49b 常用单克隆抗体或代号： Gi94;(VLA- a 2,ECMR- Ⅱ,Pt- GPIa) 主要表达细胞： Leu,Pt,Fb,En [AS] 分子
Determining Ligand Specificity of Ly49 Receptors
Ly49 receptors in rodents, like KIR in humans, play an integral role in the regulation of NK cell activity. Some inhibitory Ly49 are known to interact with specific MHC I alleles to maintain tolerance to self tissues, and NK activation
Co-Expression of human DNA primase p49-p58 subunits
Adapted from W.C.Copeland,Protein Exp.& Purif 9,(1997)1-9 and Schneider,et.al.,JBC 273:34 (1998)21608-21615. Obtained from Fanning lab and revised by LSM,7/23/01 Obtained cell stock of BL21(DE3)cells cotransformed with pET21a-Hp49 (ampicillin
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