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- 2025年12月05日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
1239602-35-7
- 规格：
10 mM * 1 mL/100 mg/250 mg/500 mg/1 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥170.0 |
|---|---|---|---|
| 规格： | 100 mg | 产品价格： | ￥155.0 |
| 规格： | 250 mg | 产品价格： | ￥310.0 |
| 规格： | 500 mg | 产品价格： | ￥510.0 |
| 规格： | 1 g | 产品价格： | ￥820.0 |
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Antibacterial agent 18
CAS No. : 1239602-35-7
MCE 国际站：Antibacterial agent 18
产品活性：Antibacterial agent 18 是一种多臂 AIE 分子，详细信息请参考专利文献 CN110123801A中的化合物 23。Antibacterial agent 18 可用于抑制革兰氏阳性和革兰氏阴性细菌的生长。Antibacterial agent 18 可以将其共轭刚性臂结构插入细菌的细胞壁中，通过阻碍转糖和转肽过程来影响细菌细胞壁合成，从而抑制或杀灭细菌。
研究领域：Anti-infection
作用靶点：Bacterial
In Vitro: Antibacterial agent 18 (0.004-4 μg/mL; 24 h) inhibits the growth of Gram-positive and Gram-negative bacteria, with MICs ranging from 0.008-1 μg/mL.
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文献和实验Genomic Approaches to Antibacterial Discovery
of concept in curing experimental infections. The second approach is based on screening for compounds with antibacterial activity and then employing a broad variety of newer technologies to identify the molecular target of the antibacterial agent
Procedure for Transfection of Mammalian Cells
IMDM containing 20% fetal bovine serum, 1% glutamine, 1% aa In a six-well or 35 mm tissue culture plate, seed ~2x 105 cells per well in 2 ml IMDM containing 10% FBS and nonessential amino acids. Incubate the cells at 37E C
Methods to Assay Inhibitors of tRNA Synthetase Activity
could be a potential antibacterial agent. Only one aa-RS inhibitor, the Ile-RS inhibitor mupirocin, is currently marketed as an antibacterial agent. We focused on phenylalanyl (Phe)-tRNA synthetase (Phe-RS), but the described methods are not restricted to Phe-RS
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