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Menthol glucuronide
CAS No. : 79466-08-3
MCE 国际站：Menthol glucuronide
产品活性：Menthol glucuronide 是 Menthol (HY-N1369) 的一种代谢物。Menthol glucuronide 可以作为作为急性吸入 Menthol 时血浆和尿液中的生物标志物。
研究领域：Metabolic Enzyme/Protease
作用靶点：Drug Metabolite
In Vitro: Menthol, a monoterpene, is a principal component of peppermint oil and is used extensively in consumer products as a flavoring aid. Menthol has a half-life of 3-6 h and is rapidly metabolized to menthol glucuronide which is detectable in urine and serum following menthol use.
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文献和实验在动物体内通过葡糖苷酸配糖体的生成所进行的解毒反应的一种。由 UDP-葡萄糖脱氢反应生成的 UDP-葡糖苷酸，其葡糖苷酸残基通过转移酶的作用向酚等的羟基转移，并生成葡糖苷酸，由尿中排出。此外，类固醇激素和胆汁色素也能形成葡糖苷酸的形式。
TRPM8 Channels as Potential Therapeutic Targets for Pain, Analgesia, and Thermoregulation
to painfully hot and from pleasingly cool to excruciatingly cold. Many of these channels are receptors for natural products that elicit distinct psychophysical sensations, such as the heat associated with capsaicin and the cold felt with menthol
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