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10 mM * 1 mL/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥429.0 |
|---|---|---|---|
| 规格： | 5 mg | 产品价格： | ￥390.0 |
| 规格： | 10 mg | 产品价格： | ￥555.0 |
| 规格： | 25 mg | 产品价格： | ￥1000.0 |
| 规格： | 50 mg | 产品价格： | ￥1400.0 |
| 规格： | 100 mg | 产品价格： | ￥2000.0 |
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MPP+ iodide
CAS No. : 36913-39-0
MCE 国际站：MPP+ iodide
产品活性：MPP+ iodide 是神经毒素 MPTP 的一种有毒代谢物，通过选择性破坏黑质多巴胺能神经元，在动物模型中引起帕金森病症状。MPP+ iodide 被多巴胺转运体吸收进入多巴胺能神经元，通过影响呼吸链复合体 I 对线粒体发挥神经毒性作用。MPP+ iodide 也是 5-羟色胺转运体 (SERT) 的高亲和力底物。
研究领域：Metabolic Enzyme/Protease
In Vitro: MPP+ (1-3 mM; 24 hours) remarkably decreases the viability of cells.
?MPP+ also inhibits the activity of nicotinamide adenosine dinucleotide (NADH)-linked respiration in mitochondrial preparations and impairs aerobic glycolysis, leading to the present belief that the inhibition of NADH-linked cell respiration may constitute the final molecular mechanism of MPP+ neurotoxicity.
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文献和实验Measurement of Oxygen Radicals and Lipid Peroxidation in Neural Tissues
Abstract Table of Contents Materials Figures Literature Cited Abstract
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