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- 2025年12月05日
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- 详细信息
- 技术资料
- 保存条件：
4°C, sealed storage, away from moisture
- 英文名：
ALO 2145
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
73218-79-8
- 规格：
10 mM * 1 mL/1 mg/5 mg/10 mg/25 mg/50 mg/100 mg
| 规格： | 10 mM * 1 mL | 产品价格： | ￥647.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥209.0 |
| 规格： | 5 mg | 产品价格： | ￥494.0 |
| 规格： | 10 mg | 产品价格： | ￥725.0 |
| 规格： | 25 mg | 产品价格： | ￥1223.0 |
| 规格： | 50 mg | 产品价格： | ￥1813.0 |
| 规格： | 100 mg | 产品价格： | ￥2675.0 |
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Apraclonidine hydrochloride
CAS No. : 73218-79-8
MCE 国际站：Apraclonidine hydrochloride
产品活性：Apraclonidine hydrochloride (ALO 2145) 是一种选择性 α2 和弱 α1 受体激动剂，能有效降低人眼压。Apraclonidine hydrochloride 是一种局部滴眼液，有提升眼睑的能力。
研究领域：GPCR/G Protein | Neuronal Signaling
作用靶点：Adrenergic Receptor
In Vitro: Apraclonidine hydrochloride (ALO 2145) is more commonly used topically for glaucoma, as it penetrates the cornea and blood-brain barrier to a lesser extent and, thus, has fewer adverse systemic effects.
In Vivo: Apraclonidine hydrochloride (ALO 2145) is effective in animal models of elevated IOP as well as glaucoma in humans. The ocular hypotensive effects of Apraclonidine are usually attributed to reduced aqueous humor synthesis and vasoconstrictor actions at the anterior segment branches of the ophthalmic artery
.Apraclonidine (1.15%, single instillation) inhibits 98% of PGE2-induced aqueous flare elevationy
.
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