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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Mouse Erythropoietin receptor (Epor), partial
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Mouse Erythropoietin receptor (Epor), partial品名简称:
Recombinant Mouse Epor protein, partial货号:
CSB-BP007744MO1规格:
20μg价格:
3168LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 90% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
EporUniprot No.:
P14753别名:
EPO-R种属:
Mus musculus (Mouse)蛋白长度:
Partial来源:
Baculovirus分子量:
26.3 kDa表达区域:
25-249aa氨基酸序列:
APSPSLPDPKFESKAALLASRGSEELLCFTQRLEDLVCFWEEAASSGMDFNYSFSYQLEGESRKSCSLHQAPTVRGSVRFWCSLPTADTSSFVPLELQVTEASGSPRYHRIIHINEVVLLDAPAGLLARRAEEGSHVVLRWLPPPGAPMTTHIRYEVDVSAGNRAGGTQRVEVLEGRTECVLSNLRGGTRYTFAVRARMAEPSFSGFWSAWSEPASLLTASDLDP蛋白标签:
C-terminal 10xHis-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.功能2:
/文献:
"Saturation mutagenesis of the WSXWS motif of the erythropoietin receptor." Hilton D.J., Watowich S.S., Katz L., Lodish H.F. J. Biol. Chem. 271:4699-4708(1996)研究领域:
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文献和实验生成素(erythropoietin,EPO)受体胞膜外区体在氨基酸序列上有较高的同源性,分子结构上也有较大的相似性,故得名。 (1)ERS的成员:属于ERS的成员有EPOR、血小板生成素R、IL-2β链(CD122)、IL-2Rγ链、IL-3Rα链(CD123)、IL-3Rβ、IIL-4R(CDw124)、IL-5Rα链、IL-5βα链、IL-5Rβ链、IL-6Rα链(CD126)、gp130(CDw123)、IL-7R、IL-9R、IL-11R、IL-1240kDa亚单位、G-CSFR、GM-CSFRα链、GM
请教一个弱智的问题, 帮忙把genebank上查的report逐个解释一下, 不要遗漏信息!
LOCUS NM_017002 1524 bp mRNA linear ROD 28-OCT-2004 DEFINITION Rattus norvegicus erythropoietin receptor (Epor), mRNA. ACCESSION NM_017002 VERSION NM_017002.1 GI:8393318 KEYWORDS . SOURCE Rattus norvegicus (Norway rat) ORGANISM Rattus
310、GM-CSFRβ链和IL-2Rγ链。 1.gp130/LIFR 为IL-6R、单抗MT18在骨髓瘤细胞系U266共沉淀中得到一种130kDa的糖蛋白,命名为gp130。1990年Hibi克隆成功,gp130,属于造血因子受体家族。IL-6、IL-11均能刺激IL-6信赖的小鼠浆细胞瘤系T1165的增殖,能在IL-3、GM-CSF的作用下缩短骨髓多能干细胞的Go期,增强IL-3依赖的人和小鼠的巨核细胞集落的形成,促进体内、体外的特异性抗体反应,诱导肝细胞急性期蛋白的产生。抗gp130
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