PDE8A抗体PDE8A兔多抗抗体Weakly simila
r to 3'5' cyclic nucleotide phosphodiesterase antibody抗体PDE8A Antibody抗体- ￥440 - 1320
- CUSABIO
- CN
- CSB-PA525315LA01HU
- 2025年07月16日
- ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
- Rabbit
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Recombinant Human High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A protein (596-829AA)
- 亚型：
IgG
- 形态：
Liquid
- 保存条件：
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性：
Polyclonal
- 标记物：
Non-conjugated
- 适应物种：
Human
- 保质期：
6个月
- 抗原来源：
Homo sapiens (Human)
- 目录编号：
O60658
- 级别：
优
- 库存：
200
- 供应商：
武汉华美生物工程有限公司
- 宿主：
Rabbit
- 应用范围：
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
- 浓度：
>95%,Antigen Affinity Purified
- 靶点：
PDE8A
- 抗体英文名：
PDE8A Antibody
- 抗体名：
Weakly similar to 3'5' cyclic nucleotide phosphodiesterase antibody
- 规格：
100μl/50μl/20μl
| 规格： | 100μl | 产品价格： | ￥1320.0 |
|---|---|---|---|
| 规格： | 50μl | 产品价格： | ￥880.0 |
| 规格： | 20μl | 产品价格： | ￥440.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes (PubMed:18983167). May be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development (PubMed:18983167). Binding to RAF1 reduces RAF1 'Ser-259' inhibitory-phosphorylation and stimulates RAF1-dependent EGF-activated ERK-signaling (PubMed:23509299). Protects against cell death induced by hydrogen peroxide and staurosporine (PubMed:23509299).风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Simm, R., Morr, M., Remminghorst, U., Andersson, M., and Römling, U. 2009. Quantitative determination of cyclic diguanosine monophosphate concentrations in nucleotide extracts of bacteria by matrix‐assisted laser desorption/ionization–
a subset of genomic DNA sequences of type 5'-(NNN )3 -3', whereas the 6ZF library would recognize a subset of genomic sequences of type 5'-(NNN )6 -3'. Given the zinc-finger domains used, both libraries were more likely to recognize (RNN)x -type sequences
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