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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
KLH conjugate of human EGFRvIII-specific, 14-amino acid peptide from the predicted amino acid sequence at the fusion junction (LEEKKGNYVVTDHC)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX02628
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Rabbit
- 应用范围:
IHC-P
- 浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
EGFR
- 抗体英文名:
EGFR antibody [GFR/2600R]
- 抗体名:
EGFR 抗体 [GFR/2600R]
- 规格:
100 μg
IHC-P analysis of human squamous cell carcinoma lung cancer section using GTX02628 EGFR antibody [GFR/2600R].
IHC-P analysis of human placenta tissue section using GTX02628 EGFR antibody [GFR/2600R].
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文献和实验本文已发表于中国肿瘤生物治疗杂志.2003,10(3):221-222.【摘要】表皮生长因子受体(Epidermal Growth Factor Receptor EGFR)是原癌基因c-erb-B1的表达产物。其过表达和突变体均与肿瘤发生发展有密切关系,基于此优点成为目前肿瘤治疗的新靶点。本文就EGFR与肿瘤的关系及其单抗治疗肿瘤的进展作一综述。【关键词】表皮生长因子受体(EGFR),单克隆抗体,肿瘤治疗【中图分类号】R730.5 [文献标识码] AEGFR monocolonal
【翻译】Development trends for monoclonal antibody cancer therapeutics
). However, since 2000, humanized and human mAbs have been entering clinical study at approximately the same rate (4.3 versus 4.5 mAbs per year, respectively). Figure 1 | Categories of monoclonal antibody cancer therapeutics entering clinical study during 1980–1989
Nature 综述导读:FDA 批准第 100 个抗体药物!抗体药物的研究方向在哪里?
仍超过 50 亿美元。 图七 Journal of Biomedical Science (2020) 27:1来自抗体协会 (Antibody Society) 的数据显示,临床管道中也存在类似的大量内卷现象。目前有将近 870 种抗体在临床开发中,但其中大约 36% 的抗体集中在下表二的 10 个靶点中。PD1/PDL1、HER2、CTLA4、EGFR 和 CD20 仍然占据较高的比例。 表二:Nature Reviews Drug Discovery 20, 10 (2021)癌症将继续占据
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