Activin Receptor Type IA Antib

产品名称：Activin Receptor Type IA Antibody-Activin Receptor Type IA Antibody

产品货号：abx033180

产品规格：80ul#400ul

应用类型：WB

保存建议：Activin Receptor Type IA Antibody-Activin Receptor Type IA Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. ACVR1 is an activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors.

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关键词：Activin Receptor Type IA Antibody，Activin Receptor Type IA Antibody，待更新