Myeloid/lymphoid Or Mixed-Line

产品名称：Myeloid/lymphoid Or Mixed-Lineage Leukemia Protein 3 (MLL3) Antibody-Myeloid/lymphoid Or Mixed-Lineage Leukemia Protein 3 (MLL3) Antibody

产品货号：abx032715

产品规格：25ul#80ul#100ul#400ul

应用类型：ELISA, WB

保存建议：Myeloid/lymphoid Or Mixed-Lineage Leukemia Protein 3 (MLL3) Antibody-Myeloid/lymphoid Or Mixed-Lineage Leukemia Protein 3 (MLL3) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL family, including MLL3. The MLL SET domain is a histone H3 Lys4 (K4) specific methyltransferase whose activity is stimulated with acetylated H3 peptides. MLL3 maps to 7q36, a chromosome region frequently deleted in myeloid leukaemia. The deduced MLL3 4911-amino acid protein is more closely related to MLL2 than to MLL1 or MLL4. MLL3 has 6 plant homeodomain (PHD) fingers preceded by a cys-rich ZNF1 domain in its N terminus; a high mobility group (HMG) box, an ATPase alpha-beta signature, and a leucine zipper motif in its central region; and 2 C-terminal FY (phe-tyr) motifs and the SET domain preceded by a ZNF2 domain in its C terminus. The predicted protein also contains several putative nuclear localization motifs. Isoform II lacks ZNF1 and the PHD.

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关键词：Myeloid/lymphoid Or Mixed-Lineage Leukemia Protein 3 (MLL3) Antibody，Myeloid/lymphoid Or Mixed-Lineage Leukemia Protein 3 (MLL3) Antibody，待更新