Tumor Suppressor ARF (MLM) Ant
ibody/Tumor Suppressor ARF (MLM) Antibody/Tumor Suppressor ARF (MLM) Antibody- 询价
- Abbexa
- 英国
- abx027077
- 2025年07月07日
- WB, IHC, FCM
- 兔
- 人
企业认证
相关产品推荐更多 >
KDM4A Antibody (HRP)/KDM4A Antibody (HRP)/KDM4A Antibody (HRP)
询价
Parvin, Alpha Polyclonal (PARVA) Antibody/Parvin, Alpha Polyclonal (PARVA) Antibody/Parvin, Alpha Polyclonal (PARVA) Antibody
询价
Sycp3 多克隆抗体 (Biotin) | Sycp3 polyclonal antibody (Biotin)
询价
ZNF699纯化的MaxPab小鼠源多克隆抗体(B01P) | ZNF699 purified MaxPab mouse polyclonal antibody (B01P)
询价
Rabbit GIPR Antibody/Rabbit GIPR Antibody
询价
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
MLM
- 亚型：
Tumor Suppressor ARF (MLM) Antibody
- 形态：
Tumor Suppressor ARF (MLM) Antibody
- 保存条件：
建议收到产品后，储存温度为-20°C。避免重复冻融
- 克隆性：
见产品详情页面
- 标记物：
无
- 适应物种：
人
- 保质期：
根据订购时间与产品批次判定，欢迎联系艾美捷咨询确认
- 抗原来源：
重组蛋白
- 目录编号：
abx027077
- 级别：
见产品详情页面
- 库存：
见产品详情页面
- 供应商：
艾美捷
- 宿主：
兔
- 应用范围：
WB, IHC, FCM
- 浓度：
关于浓度，请联系艾美捷客服确认
- 靶点：
MLM
- 抗体英文名：
Tumor Suppressor ARF (MLM) Antibody
- 抗体名：
MLM
- 规格：
80ul///400ul
产品名称：Tumor Suppressor ARF (MLM) Antibody-Tumor Suppressor ARF (MLM) Antibody
产品货号：abx027077 产品规格：80ul#400ul 应用类型：WB, IHC, FCM
保存建议：Tumor Suppressor ARF (MLM) Antibody-Tumor Suppressor ARF (MLM) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融
背景资料：This gene generates several transcript variants which differ in their first exons. At least three alternatively spliced variants encoding distinct proteins have been reported, two of which encode structurally related isoforms known to function as inhibitors of CDK4 kinase. The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene; this transcript contains an alternate open reading frame (ARF) that specifies a protein which is structurally unrelated to the products of the other variants. This ARF product functions as a stabilizer of the tumor suppressor protein p53 as it can interact with, and sequester, MDM1, a protein responsible for the degradation of p53. In spite of the structural and functional differences, the CDK inhibitor isoforms and the ARF product encoded by this gene, through the regulatory roles of CDK4 and p53 in cell cycle G1 progression, share a common functionality in cell cycle G1 control. This gene is frequently mutated or deleted in a wide variety of tumors, and is known to be an important tumor suppressor gene.
点击：Tumor Suppressor ARF (MLM) Antibody-Tumor Suppressor ARF (MLM) Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询Abbexa中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品网站。
Abbexa总部位于英国剑桥的剑桥科学园，是一家专业的全球抗体供应商和蛋白质供应商，致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究，药物开发，疾病研究还是其它生物学研究，Abbexa的单克隆抗体，多克隆抗体，蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求，Abbexa还提供了定制蛋白质，肽和抗体的生产渠道。
艾美捷科技与国内外优秀的生物试剂供应商优保持着密切的合作关系，目前已成为众多国际知名品牌的中国总代理或一级代理，主要包括：AmyJet、AAT Bioquest、Abbexa、Abnova、Agrisera、Anogen、Biosensis、Biovision、Caisson Labs、Cayman Chemical、Cell Biolabs、Cytoskeleton、Demeditec、Duchefa、Epigentek、Equitech-Bio、EXBio、Fitzgerald、GeneCopoeia、Hycult Biotech、ImmunoReagents、ImmunoStep、Jackson、LifeSensors、LigaTrap、Mabtech、Matreya、Norgen Biotek、Origene、ProImmune、ProSpec、ScyTek、Solis BioDyne、SouthernBiotech、StressMarq、SySy、US Biological、TRC等，可以在短时间内为用户提供专业的前沿资讯、完备的产品及物流服务。
关键词：Tumor Suppressor ARF (MLM) Antibody，Tumor Suppressor ARF (MLM) Antibody，待更新
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验The Regulation of Tumor Suppressor Genes by Oncogenes
Tumor suppressor genes (TSGs) and oncogenes represent the ying and the yang of cell growth, differentiation, and survival control. TSGs such as p53, the retinoblastoma (RB) gene product, and the cyclin kinase inhibitor (CKI) proteins p21 Cip
Microarray Approaches for Analysis of Tumor Suppressor Gene Function
Many tumor suppressor genes are known to function at least in part through regulation of the transcription of downstream effector genes (Table 1 ). A major example of such a transcriptional regulator is p53, one of the most commonly mutated
Identification of DNA-Binding of Tumor Suppressor Genes by Chromatin Immunoprecipitation
fragment with the protein upon antibody binding. Here we describe a protocol for the immunoprecipitation of transcription factors bound to promoter sequences in cells, and use the p53 tumor suppressor as an example (Fig. 1 ). Fig. 1.
技术资料暂无技术资料 索取技术资料
