F-Box/WD Repeat-Containing Pro

产品名称：F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody-F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody

产品货号：abx026481

产品规格：80ul#400ul

应用类型：IF/ICC

保存建议：F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody-F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class; in addition to an F-box, this protein contains multiple WD-40 repeats. This protein is homologous to Xenopus bTrCP1, yeast Met30, Neurospora Scon2 and Drosophila Slimb proteins. It interacts with HIV-1 Vpu and connects CD4 to the proteolytic machinery. It also associates specifically with phosphorylated IkappaBalpha and beta-catenin destruction motifs, probably functioning in multiple transcriptional programs by activating the NF-kappaB pathway and inhibiting the beta-catenin pathway.

点击：F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody-F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询Abbexa中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品网站。

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关键词：F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody，F-Box/WD Repeat-Containing Protein 1A (BTRC) Antibody，待更新