Histone Acetyltransferase Type

产品名称：Histone Acetyltransferase Type B Catalytic Subunit (KAT1) Antibody-Histone Acetyltransferase Type B Catalytic Subunit (KAT1) Antibody

产品货号：abx025916

产品规格：80ul#400ul

应用类型：WB

保存建议：Histone Acetyltransferase Type B Catalytic Subunit (KAT1) Antibody-Histone Acetyltransferase Type B Catalytic Subunit (KAT1) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells. HAT1 may play a role in telomeric silencing.

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关键词：Histone Acetyltransferase Type B Catalytic Subunit (KAT1) Antibody，Histone Acetyltransferase Type B Catalytic Subunit (KAT1) Antibody，待更新