Methyl-CpG Binding Domain Prot
ein 2 (MBD2) Antibody/Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody/Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody- 询价
- Abbexa
- 英国
- abx025844
- 2025年07月16日
- WB
- 兔
- 人，小鼠
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TAOK1 抗体（pTyr309）：偶联ATTO 594|TAOK1 Antibody (pTyr309): ATTO 594
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
MBD2
- 亚型：
Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody
- 形态：
Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody
- 保存条件：
建议收到产品后，储存温度为-20°C。避免重复冻融
- 克隆性：
见产品详情页面
- 标记物：
无
- 适应物种：
人，小鼠
- 保质期：
根据订购时间与产品批次判定，欢迎联系艾美捷咨询确认
- 抗原来源：
重组蛋白
- 目录编号：
abx025844
- 级别：
见产品详情页面
- 库存：
见产品详情页面
- 供应商：
艾美捷
- 宿主：
兔
- 应用范围：
WB
- 浓度：
关于浓度，请联系艾美捷客服确认
- 靶点：
MBD2
- 抗体英文名：
Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody
- 抗体名：
MBD2
- 规格：
80ul///400ul
产品名称：Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody-Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody
产品货号：abx025844 产品规格：80ul#400ul 应用类型：WB
保存建议：Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody-Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融
背景资料：DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. Human proteins MECP2, MBD1, MBD2, MBD3, and MBD4 comprise a family of nuclear proteins related by the presence in each of a methyl-CpG binding domain (MBD). Each of these proteins, with the exception of MBD3, is capable of binding specifically to methylated DNA. MECP2, MBD1 and MBD2 can also repress transcription from methylated gene promoters. The protein encoded by this gene may function as a mediator of the biological consequences of the methylation signal. It is also reported that the this protein functions as a demethylase to activate transcription, as DNA methylation causes gene silencing.
点击：Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody-Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询Abbexa中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品网站。
Abbexa总部位于英国剑桥的剑桥科学园，是一家专业的全球抗体供应商和蛋白质供应商，致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究，药物开发，疾病研究还是其它生物学研究，Abbexa的单克隆抗体，多克隆抗体，蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求，Abbexa还提供了定制蛋白质，肽和抗体的生产渠道。
艾美捷科技与国内外优秀的生物试剂供应商优保持着密切的合作关系，目前已成为众多国际知名品牌的中国总代理或一级代理，主要包括：AmyJet、AAT Bioquest、Abbexa、Abnova、Agrisera、Anogen、Biosensis、Biovision、Caisson Labs、Cayman Chemical、Cell Biolabs、Cytoskeleton、Demeditec、Duchefa、Epigentek、Equitech-Bio、EXBio、Fitzgerald、GeneCopoeia、Hycult Biotech、ImmunoReagents、ImmunoStep、Jackson、LifeSensors、LigaTrap、Mabtech、Matreya、Norgen Biotek、Origene、ProImmune、ProSpec、ScyTek、Solis BioDyne、SouthernBiotech、StressMarq、SySy、US Biological、TRC等，可以在短时间内为用户提供专业的前沿资讯、完备的产品及物流服务。
关键词：Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody，Methyl-CpG Binding Domain Protein 2 (MBD2) Antibody，待更新
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文献和实验Enrichment of Methylated DNA by Methyl-CpG Immunoprecipitation
to methylated DNA. Methyl-CpG Immunoprecipitation (MCIp) employs an immobilized recombinant human methyl-CpG binding domain protein 2, MBD2, which binds methylated CpGs in double-stranded DNA. Elution with increasing salt concentrations allows the fractionated
of methyl′CpG binding proteins was described 7 . The five members of this family share a similar methyl′CpG binding domain. One of these proteins, MeCP2, is known to be necessary for embryonic development, although the effects on imprinted genes
Methyl DNA Immunoprecipitation
or sequencing, involving time- and labor-intensive chemical treatments that damage DNA and limit throughput. It was shown that the methyl-binding domain (MBD) of MeCP2 has some sequence preference besides its recognition of methyl-CpGs (10 ) and that the MBD
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