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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
CDKN2D
- 亚型:
Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody
- 形态:
Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody
- 保存条件:
建议收到产品后,储存温度为-20°C。避免重复冻融
- 克隆性:
见产品详情页面
- 标记物:
无
- 适应物种:
人
- 保质期:
根据订购时间与产品批次判定,欢迎联系艾美捷咨询确认
- 抗原来源:
重组蛋白
- 目录编号:
abx005030
- 级别:
见产品详情页面
- 库存:
见产品详情页面
- 供应商:
艾美捷
- 宿主:
兔
- 应用范围:
WB, IF/ICC
- 浓度:
关于浓度,请联系艾美捷客服确认
- 靶点:
CDKN2D
- 抗体英文名:
Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody
- 抗体名:
CDKN2D
- 规格:
20ul///50ul///100ul///200ul
产品名称:Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody-Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody
产品货号:abx005030 产品规格:20ul#50ul#100ul#200ul 应用类型:WB, IF/ICC
保存建议:Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody-Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody建议收到产品后,储存温度为-20°C。避免重复冻融
背景资料:CDKN2D Antibody is a Rabbit Polyclonal antibody against CDKN2D. The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.
点击:Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody-Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询Abbexa中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品网站。
Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究,药物开发,疾病研究还是其它生物学研究,Abbexa的单克隆抗体,多克隆抗体,蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求,Abbexa还提供了定制蛋白质,肽和抗体的生产渠道。
艾美捷科技与国内外优秀的生物试剂供应商优保持着密切的合作关系,目前已成为众多国际知名品牌的中国总代理或一级代理,主要包括:AmyJet、AAT Bioquest、Abbexa、Abnova、Agrisera、Anogen、Biosensis、Biovision、Caisson Labs、Cayman Chemical、Cell Biolabs、Cytoskeleton、Demeditec、Duchefa、Epigentek、Equitech-Bio、EXBio、Fitzgerald、GeneCopoeia、Hycult Biotech、ImmunoReagents、ImmunoStep、Jackson、LifeSensors、LigaTrap、Mabtech、Matreya、Norgen Biotek、Origene、ProImmune、ProSpec、ScyTek、Solis BioDyne、SouthernBiotech、StressMarq、SySy、US Biological、TRC等,可以在短时间内为用户提供专业的前沿资讯、完备的产品及物流服务。
关键词:Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody,Cyclin Dependent Kinase Inhibitor 2D (CDKN2D) Antibody,待更新
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文献和实验Assays for Cyclin-Dependent Kinase Inhibitors
Cyclin-dependent kinases (CDK) are serine/threonine kinases that regulate cell cycle control and progression (1 ,2 ). A CDK holoenzyme complex is active if associated with its cyclin partner and if the complex is phosphorylated at specific
Orderly progression of the eukaryotic cell cycle is governed by a coordinated response to intrinsic and extracellular cues through activation of cyclin-dependent kinases (CDKs). It is therefore important to verify the kinase activity
3 篇 Nature 连发,解决世纪难题,周期蛋白的毁灭调控蕴含癌症患者的新生
细胞周期是细胞生命活动的基本过程,受到细胞内外信号交互作用的精密调控。D 型细胞周期蛋白 (cyclin D1, D2 和 D3) 与细胞周期蛋白依赖性激酶(cyclin-dependent kinases,CDKs)是整个细胞周期调控机制中的核心分子,驱动细胞增殖。细胞周期失调是人类癌症的一个共同特征,其中 cyclin D-CDK4/6 复合物的水平和活性与不受约束的细胞增殖密切相关。自从 20 世纪 90 年代发现 cyclin D 以来,人们就对其进行了深入研究,但是关于 cyclin
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