G1/S-Specific Cyclin-E1 Phosph

产品名称：G1/S-Specific Cyclin-E1 Phospho-Thr395 (CCNE1 pT395) Antibody-G1/S-Specific Cyclin-E1 Phospho-Thr395 (CCNE1 pT395) Antibody

产品货号：abx000102

产品规格：20ul#50ul#100ul#200ul

应用类型：WB, IF/ICC

保存建议：G1/S-Specific Cyclin-E1 Phospho-Thr395 (CCNE1 pT395) Antibody-G1/S-Specific Cyclin-E1 Phospho-Thr395 (CCNE1 pT395) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：CCNE1 (pT395) Antibody is a Rabbit Polyclonal antibody against CCNE1 (pT395). The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. Two alternatively spliced transcript variants of this gene, which encode distinct isoforms, have been described. Two additional splice variants were reported but detailed nucleotide sequence information is not yet available.

点击：G1/S-Specific Cyclin-E1 Phospho-Thr395 (CCNE1 pT395) Antibody-G1/S-Specific Cyclin-E1 Phospho-Thr395 (CCNE1 pT395) Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询Abbexa中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品网站。

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关键词：G1/S-Specific Cyclin-E1 Phospho-Thr395 (CCNE1 pT395) Antibody，G1/S-Specific Cyclin-E1 Phospho-Thr395 (CCNE1 pT395) Antibody，待更新